When picking or editing a gaming or anime PFP, focus on a clear silhouette and...

https://purepfp.com/why-bold-game-characters-remain-recognisable-in-tiny-profile-icons/

When picking or editing a gaming or anime PFP, focus on a clear silhouette and high contrast to make your icon stand out even tiny. Crop tightly on the face and keep backgrounds simple—avoid text since it’s hard to read